@article {588,
	title = {A new approach for the detection of a nonfluorescent compound by CE-resonance Raman spectroscopy based on the sweeping-MEKC mode},
	journal = {Electrophoresis},
	volume = {27},
	number = {23},
	year = {2006},
	note = {<p>117WCTimes Cited:9Cited References Count:27</p>
},
	month = {Dec},
	pages = {4688-4693},
	abstract = {<p>A CE-resonance Raman spectroscopy (CE-RRS) method based on MEKC and sweeping-MEKC modes is described. A nonfluorescent compound, malachite green (MG), and a doubled Nd:YAG laser (532 nm, 300 mW) were selected as model compound and light source, respectively. In order to carry out a quantitative analysis of MG, a monochromator (effective bandwidth, 0.4 nm) was used to collect the specific Raman line at 1616 cm(-1) (N-phi and C-C stretch, corresponding to 582 nm when the wavelength of the exciting source was 532 nm). As a result, the LOD for MG was 10 ppm, based on the MEKC/RRS mode. This could be improved to 5 ppb when the sweeping-MEKC/RRS mode was applied. Furthermore, with the addition of nano-size silver colloids to the CE buffer the detection limits can be further improved, but the data obtained with surface-enhanced resonance Raman spectroscopy (SERRS) are less useful for quantitative purposes.</p>
},
	keywords = {capillary-electrophoresis, ce, dynamic ph junction, fluorescence detection, identification, leucomalachite green, malachite green, mass-spectrometry, performance liquid-chromatography, raman spectroscopy, SCATTERING, stacking, surface enhanced-resonance raman spectroscopy, sweeping-mekc},
	isbn = {0173-0835},
	url = {<Go to ISI>://WOS:000242903000011},
	author = {Tsai, C. H. and Chan, P. H. and Lin, C. H. and Chang, T. C. and Chia, C. T.}
}
