<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Chao, M.-H.</style></author><author><style face="normal" font="default" size="100%">Lin, Y.-T.</style></author><author><style face="normal" font="default" size="100%">Dhenadhayalan, N.</style></author><author><style face="normal" font="default" size="100%">Lee, H.-L.</style></author><author><style face="normal" font="default" size="100%">H.-Y. Lee</style></author><author><style face="normal" font="default" size="100%">Lin, K.-C.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">3D Probed Lipid Dynamics in Small Unilamellar Vesicles</style></title><secondary-title><style face="normal" font="default" size="100%">Small</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">Autocorrelation analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Cholesterol</style></keyword><keyword><style  face="normal" font="default" size="100%">chromophores</style></keyword><keyword><style  face="normal" font="default" size="100%">DEFECTS</style></keyword><keyword><style  face="normal" font="default" size="100%">DYNAMICS</style></keyword><keyword><style  face="normal" font="default" size="100%">Fluorescence</style></keyword><keyword><style  face="normal" font="default" size="100%">Fluorescence spectroscopy</style></keyword><keyword><style  face="normal" font="default" size="100%">Kinetic information</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipid bilayers</style></keyword><keyword><style  face="normal" font="default" size="100%">Lipid dynamics</style></keyword><keyword><style  face="normal" font="default" size="100%">MOLECULES</style></keyword><keyword><style  face="normal" font="default" size="100%">Optical correlation</style></keyword><keyword><style  face="normal" font="default" size="100%">Single molecule fluorescence</style></keyword><keyword><style  face="normal" font="default" size="100%">Single molecule level</style></keyword><keyword><style  face="normal" font="default" size="100%">Small unilamellar vesicle</style></keyword><keyword><style  face="normal" font="default" size="100%">Spectroscopic analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Synchrotrons</style></keyword><keyword><style  face="normal" font="default" size="100%">Triplet state lifetime</style></keyword><keyword><style  face="normal" font="default" size="100%">Unilamellar vesicle</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2017</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://www.scopus.com/inward/record.uri?eid=2-s2.0-85017105024&amp;doi=10.1002%2fsmll.201603408&amp;partnerID=40&amp;md5=ae4b458e0331d91b36bb62a309b8af6b</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">13</style></number><volume><style face="normal" font="default" size="100%">13</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p&gt;Single-molecule fluorescence correlation spectroscopy overcomes the resolution barrier of optical microscopy (10≈–20 nm) and is utilized to look into lipid dynamics in small unilamellar vesicles (SUVs; diameter &amp;lt; 100 nm). The fluorescence trajectories of lipid-like tracer 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindodicarbocyanine (DiD) in the membrane bilayers are acquired at a single-molecule level. The autocorrelation analysis yields the kinetic information on lipid organization, oxygen transport, and lateral diffusion in SUVs' membrane. First, the isomerization feasibility may be restricted by the addition of cholesterols, which form structure conjugation with DiD chromophore. Second, the oxygen transport is prevented from the ultrasmall cluster and cholesterol-rich regions, whereas it can pass through the membrane region with liquid-disordered phase (Ld) and defects. Third, by analyzing 2D spectra correlating the lipid diffusion coefficient and triplet-state lifetime, the heterogeneity in lipid bilayer can be precisely visualized such as lipid domain with different phases, the defects of lipid packing, and DiD-induced “bouquet” ultrasmall clusters. © 2017 WILEY-VCH Verlag GmbH &amp;amp; Co. KGaA, Weinheim&lt;/p&gt;
</style></abstract><notes><style face="normal" font="default" size="100%">&lt;p&gt;cited By 2&lt;/p&gt;
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