@article {Dhenadhayalan201623953,
	title = {Silicon Quantum Dot-Based Fluorescence Turn-On Metal Ion Sensors in Live Cells},
	journal = {ACS Applied Materials and Interfaces},
	volume = {8},
	number = {36},
	year = {2016},
	note = {<p>cited By 10</p>
},
	pages = {23953-23962},
	abstract = {<p>Multiple sensor systems are designed by varying aza-crown ether moiety in silicon quantum dots (SiQDs) for detecting individual Mg2+, Ca2+, and Mn2+ metal ions with significant selectivity and sensitivity. The detection limit of Mg2+, Ca2+, and Mn2+ can reach 1.81, 3.15, and 0.47 μM, respectively. Upon excitation of the SiQDs which are coordinated with aza-crown ethers, the photoinduced electron transfer (PET) takes place from aza-crown ether moiety to the valence band of SiQDs core such that the reduced probability of electron-hole recombination may diminish the subsequent fluorescence. The fluorescence suppression caused by such PET effect will be relieved after selective metal ion is added. The charge-electron binding force between the metal ion and aza-crown ether hinders the PET and thereby restores the fluorescence of SiQDs. The design of sensor system is based on the fluorescence "turn-on" of SiQDs while in search of the appropriate metal ion. For practical application, the sensing capabilities of metal ions in the live cells are performed and the confocal image results reveal their promising applicability as an effective and nontoxic metal ion sensor. {\textcopyright} 2016 American Chemical Society.</p>
},
	keywords = {Aza-crown-ether, Bio-imaging, Calcium, cell survival, crown ether, Crown ethers, Electron transitions, Electron-hole recombination, ELECTRONS, Ethers, Fluorescence, Fluorescence suppression, ion, Ions, Ligands, Manganese, METAL, Metal ions, METALS, Multiple sensor systems, Nanocrystals, Negative ions, Photo-induced electron transfer, quantum dot, quantum dots, Selectivity and sensitivity, Semiconductor quantum dots, Sensors, Silicon, Silicon quantum dots},
	doi = {10.1021/acsami.6b07789},
	url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84987738953\&doi=10.1021\%2facsami.6b07789\&partnerID=40\&md5=102427c9edc5b378a63d40986eadd06a},
	author = {Dhenadhayalan, N. and Lee, H.-L. and K. Yadav and Lin, K.-C. and Lin, Y.-T. and A.H.H. Chang}
}
