臺菲(PH)雙邊協議型擴充加值(add-on) 國際合作研究計畫－利用多維金屬氧化物的氣體感應器偵測揮發性有機物質在呼吸系統的應用(1/2)
Project Title:臺菲(PH)雙邊協議型擴充加值(add-on) 國際合作研究計畫－利用多維金屬氧化物的氣體感應器偵測揮發性有機物質在呼吸系統的應用(1/2)
Funding Organization: Ministry of Science and Technology
Project Number: 108-2923-M-002-003-
Start & Expected Completion date: 2019/10/01-2020/09/30
Keywords:
Abstract:
Respiration rate is a valuable indicator of the current condition of the respiratory system which can predict the presence of infections or serious complications. The traditional measurement of respiration rate involves manual observation of the rate of breathing using stethoscope which is limited by inter-observer reliability and method of accuracy. Other most commonly used methods of monitoring the respiration rate include electromyography from respiratory muscles, capnography, and pneumotachograph which requires additional invasive procedures. On the other hand, volatile organic compounds (VOC) which are present in exhaled human breath has been associated with some latent or active respiratory illnesses. For example, using gas chromatography-mass spectrometry, reports have identified VOC present in the exhaled breath of patients with Active Pulmonary Tuberculosis that is not present in healthy people. Present diagnostics are expensive and complicated for use as a point-of-care- detection tool. The use of gas sensors, on the other hand, makes it simple, cheap, non-invasive with direct access to physiological and non-physiological parameters. This study proposes the use of metal oxide nanomaterials such as SnO2 and ZnO in the fabrication of a VOC gas sensor. Many studies have been made on metal oxide nanomaterials since it can form various structural geometries with an electronic structure that can exhibit metallic, semiconductor, or insulator characteristics. Metal oxides possess exceptional potential as base materials in emerging technologies
From Stereodynamic Imaging, Roaming Signature, Halogen Elimination to Lipid Dynamics at a Single-Molecule Leve（1/3）
Project Title: From Stereodynamic Imaging, Roaming Signature, Halogen Elimination to Lipid Dynamics at a Single-Molecule Leve（1/3）
Funding Organization:
Project Number: 108-2113-M-002-008-
Start & Expected Completion date: 2019/08/01 - 2020/07/31
Keyword：Orientation; Photodissociation; Roaming mechanism
Abstract：
In this three-year proposal, we plan to conduct four projects:
1. Stereodynamic imaging of photofragments from oriented chiral molecules,
2. Roaming signature in photodissociation of carbonyl compounds in conjunction with hexapole state selector,
3. Hetero-halogen elimination and halogen-channel competition by cavity ring-down absorption spectroscopy, and
4. Liposome dynamics probed by single-molecule fluorescence correlation spectroscopy: dependence of vesicle size and structure phase.
In the first subject, we will focus on differentiation of 2-bromobutane enantiomers in S- and R-form. A sliced ion imaging will be applied for photofragment detection, while the individual enantiomer is oriented with hexapole state selector coupled with DC field. A single or dual lasers experiment will be carried out for photodissociation of enantiomer,followed by (2+1) REMPI acquisition of either Br or Br*. Then, the ion images will be analyzed to obtain recoil frame angles and the subsequent photofragment angular distribution for chirality recognition.
In the second subject, we plan to apply a photolysis-probe technique to CH3CHO molecules which will be oriented with hexapole state selector. Following photolysis at 248 nm, the CO fragment will be probed with (2+1) REMPI scheme at ~230 nm. The J-dependence of translational energy distribution will be analyzed in comparison with the results but without molecular orientation. Meanwhile, in collaboration with Bowman and Han, the QCT calculations on a full dimensional PES will be performed according to the experimental conditions.
In the third project, we will carry out photodissociation of CHBr2I at 248 nm followed by spectral acquisition of Br2 and BrI fragments using CRDS. First of all, we will collaborate with Prof. Liang group to synthesize the compound which will be separated and purified to remove side-products to the minimum extent. Then, we will analyze the rovibrational spectra of these two fragments and evaluate the branching ratio of each fragment. From the theoretical point of view, we will estimate the branching ratio of these two fragments for comparison with the experimental value and then elucidate the results.
In the fourth project, we will synthesize two types of SUVs, DPPC and DOPC, with various vesicle sizes from 10 to 100 nm with involvement of silica bead. We will look into influence of vesicle size on the diffusion properties of the SUVs and the DiD triplet state lifetime. Following the similar experiments, the lipid dynamics of DPPC and DOPC with different phase will be studied. A similar plot of diffusion rate versus triplet lifetime will be analyzed and compared between different lipid composition to find out phase influence on the photodynamic and diffusion properties of DiD in SUVs.
均勻佈植奈米貴金屬之微米碳球：提升高分子正溫度係數保護元件之導電性及穩定度(2/2)
Project Title: 均勻佈植奈米貴金屬之微米碳球：提升高分子正溫度係數保護元件之導電性及穩定度(2/2)
Funding Organization: Ministry of Science and Technology; Polytronics Technology Corp. (PTTC)
Project Number: 108-2622-M-002-004-CC1
Start & Expected Completion date: 2019/11/01-2020/10/31
Keywords: Nanomaterials；Carbon materials； Metal nanoparticles；Polymeric positive temperature coefficient protector,；Polymers
Abstract:
We present a one-year proposal regarding “Well-dispersed Noble Metal Nanoparticles on Carbon Microdot: Enhancement of Conductivity and Stability of Polymeric Positive Temperature Coefficient Protector (PPTCP)” which is divided into four subjects including, 1. Synthesis and functionalization of biowaste derived carbon nanomaterials to utilize in the application of PPTCP, 2. Fabrication of polymer supported carbon-based nanocomposite for practical applications, 3. Synthesis of highly dispersed metal nanoparticles stabilized with carbon nanomaterials, and 4. Development of transition metal dichalcogenides nanosheets mixed with polymer/carbon nanomaterials. This proposal is mainly focused on the development of different kind of carbon nanomaterials. In addition, the prepared nanomaterials will be functionalized with many different materials such as polymers, metal nanoparticles, transition metals, and so on. Then, functionalized nanomaterials will be characterized by using various analytical techniques; moreover the fundamental photoprocesses including absorption and fluorescence will be characterized. Finally, the functionalized carbon nanomaterials will be utilized to the PPTCP and various applications.